Crushing the Cancer Curveball - Kicking Cancer's Ass Podcast

Crushing the Cancer Curveball - Kicking Cancer's Ass Podcast

What the minimum effective dose means for you and what to ask your doctor

Why "Less" Might Be Exactly What You Need to Stay Protected

Joelle Kaufman's avatar
Joelle Kaufman
Mar 18, 2026
∙ Paid

The standard dose of tamoxifen has been 20mg daily for five years since the 1980s. That dose was established because it worked in trials and it was safe, not because anyone asked whether a lower dose might work just as well with a fraction of the consequences. For decades, no one seriously ran that trial.

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